Anti-Phospho-LRP6 (Ser1490) antibody-磷酸化低密度脂蛋白受体相关蛋白6抗体

Rabbit  Anti-Phospho-LRP6 (Ser1490) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Phospho-LRP6 (Ser1490)

IR:Immunogen Range:P(p-S)PA

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4040

Swiss Prot:O75581

Source:KLH conjugated synthesised phosphopeptide derived from human LRP6 around the phosphorylation site of Ser1490:P(p-S)PA 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！