Anti-phospho-TGF beta Receptor II (Tyr259) antibody-磷酸化转移生长因子β受体2抗体

Rabbit  Anti-phospho-TGF beta Receptor II (Tyr259) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-TGF beta Receptor II (Tyr259)

IR:Immunogen Range:EV(p-Y)KA

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:7048

Swiss Prot:P37173

Source:KLH conjugated synthesised phosphopeptide derived from human TGF beta Receptor II around the phosphorylation site of Tyr259:EV(p-Y)KA 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！