Anti-Claudin 15 antibody-紧密连接蛋白15抗体

Rabbit  Anti-Claudin 15 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Claudin 15

IR:Immunogen Range:101-180/228

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:24146

Swiss Prot:P56746

Source:KLH conjugated synthetic peptide derived from human Claudin 15:101-180/228 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-15 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
.

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！