Anti-C5R1 antibody-补体成分5受体1抗体

Rabbit  Anti-C5R1 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:C5R1

IR:Immunogen Range:51-150/350

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:728

Swiss Prot:P21730

Source:KLH conjugated synthetic peptide derived from human C5R1:51-150/350 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Rat
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！