Anti-Perforin antibody-穿孔素抗体

Rabbit  Anti-Perforin Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Perforin

IR:Immunogen Range:22-100/555

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5551

Swiss Prot:P14222

Source:KLH conjugated synthetic peptide derived from human Perforin:22-100/555 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Horse

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！