Anti-CaMKII delta antibody-钙/钙调素依赖蛋白激酶2D(CaMKIIδ)抗体

Rabbit  Anti-CaMKII delta Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:CaMKII delta

IR:Immunogen Range:271-370/499

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:817

Swiss Prot:Q13557

Source:KLH conjugated synthetic peptide derived from Human CAMK2D/CaMKII delta:271-370/499 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated å, ∫, © and ∂, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but phosphorylation by a CaMK is also required for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Mouse
Rat
Pig
Cow

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！