Anti-Lamin B (Nuclear Loading Control) antibody-核纤层蛋白B(核内参)抗体

Rabbit  Anti-Lamin B (Nuclear Loading Control) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Lamin B (Nuclear Loading Control)

IR:Immunogen Range:171-270/586

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4001

Swiss Prot:P20700

Source:KLH conjugated synthetic peptide derived from human Lamin B:171-270/586 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Sheep

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！