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  • Anti-Cullin 3 antibody-Cullin3抗体

Anti-Cullin 3 antibody-Cullin3抗体

Cullin 3
1138 50ul 起订
1880 100ul 起订
2900 200ul 起订
上海 更新日期:2024-08-16

上海沪震实业有限公司

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联系人:陈环环
电话:021-60345367拨打
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邮箱:sales@shzbio.com

产品详情:

中文名称:
Anti-Cullin 3 antibody-Cullin3抗体
英文名称:
Cullin 3
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
CUL 3; Cul-3; CUL3; CUL3_HUMAN; Cullin-3; Cullin3; KIAA0617.
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
ELISA=1:5000-10000 IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG
免疫原:
详见说明书
货号:
Hz-R4211
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
ELISA=1:5000-10000 IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Rabbit  Anti-Cullin 3 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Cullin 3

IR:Immunogen Range:411-510/768

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:8452

Swiss Prot:Q13618

Source:KLH conjugated synthetic peptide derived from human Cullin 3:411-510/768 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the susbstrate recognition component. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, H2AFY and DAXX, and probably GLI2 or GLI3. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. Involved in ubiquitination of cyclin E and of cyclin D1 (in vitro) thus involved in regulation of G1/S transition.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit

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仅供科研使用。不能用于人和动物治疗等其它临床诊断用!

Cullin 3;CUL 3;Cul-3;CUL3;Cullin-3;Cullin3;KIAA0617;CUL3_HUMAN;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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