Anti-phospho-STAT5a (Ser726) antibody-磷酸化信号转导和转录激活因子5a抗体

Rabbit  Anti-phospho-STAT5a (Ser726) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-STAT5a (Ser726)

IR:Immunogen Range:AP(p-S)PA

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6776

Swiss Prot:P42229

Source:KLH conjugated Synthesised phosphopeptide derived from human STAT5a around the phosphorylation site of Ser726:AP(p-S)PA 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！