Anti-BLNK antibody-B淋巴细胞连接蛋白抗体

Rabbit  Anti-BLNK Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:BLNK

IR:Immunogen Range:301-400/456

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:29760

Swiss Prot:Q8WV28

Source:KLH conjugated synthetic peptide derived from human BLNK:301-400/456 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1μg /test)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！