Anti-phospho-ALK (Tyr1604) antibody-磷酸化间变型淋巴瘤激酶抗体

Rabbit  Anti-phospho-ALK (Tyr1604) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-ALK (Tyr1604)

IR:Immunogen Range:GH(p-Y)ED

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:238

Swiss Prot:Q9UM73

Source:KLH conjugated Synthesised phosphopeptide derived from human ALK around the phosphorylation site of Tyr1604:GH(p-Y)ED 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), LK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011].

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg /test)
IF(1:100-500)

Cross Reactive Species:Human
Pig
Guinea Pig

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！