Anti-Angiotensin II antibody-血管紧张素Ⅱ抗体

Rabbit  Anti-Angiotensin II Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Angiotensin II

IR:Immunogen Range:

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:183

Swiss Prot:P01019

Source:(DRVYIHPF-GG)8K4K2KG: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
Sheep

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！