Anti-Perilipin 1 antibody-脂滴包被蛋白Perilipin-A抗体

Rabbit  Anti-Perilipin 1 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Perilipin 1

IR:Immunogen Range:331-430/522

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5346

Swiss Prot:O60240

Source:KLH conjugated synthetic peptide derived from human Perilipin-1:331-430/522 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 2–6 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(5μg/Test)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Sheep

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！