Anti-phospho-Girdin (Ser1417) antibody-磷酸化肌动蛋白结合蛋白Girdin抗体 新品

Rabbit  Anti-phospho-Girdin (Ser1417) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-Girdin (Ser1417)

IR:Immunogen Range:QK(p-S)LT

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:55704

Swiss Prot:Q3V6T2

Source:KLH conjugated synthesised phosphopeptide derived from human APE around the phosphorylation site of Ser1417:QK(p-S)LT 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1ug/test)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！