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网站主页 磷酸化肿瘤抑制基因LATS1/LATS2抗体 Anti-phospho-LATS1+LATS2 (Thr1079 +Thr1041) antibody-磷酸化肿瘤抑制基因LATS1/LATS2抗体
  • Anti-phospho-LATS1+LATS2 (Thr1079 +Thr1041) antibody-磷酸化肿瘤抑制基因LATS1/LATS2抗体

Anti-phospho-LATS1+LATS2 (Thr1079 +Thr1041) antibody-磷酸化肿瘤抑制基因LATS1/LATS2抗体

phospho-LATS1+LATS2 (Thr1079 +Thr1041)
1280 50ul 起订
1980 100ul 起订
2900 200ul 起订
上海 更新日期:2024-08-14

上海沪震实业有限公司

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联系人:陈环环
电话:021-60345367拨打
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产品详情:

中文名称:
Anti-phospho-LATS1+LATS2 (Thr1079 +Thr1041) antibody-磷酸化肿瘤抑制基因LATS1/LATS2抗体
英文名称:
phospho-LATS1+LATS2 (Thr1079 +Thr1041)
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
LATS1 +LATS2 (phospho T1079 + T1041); Serine/threonine protein kinase LATS2; KPM; Large tumor supressor, homolog 1; LATS, large tumor suppressor, homolog 1 (Drosophila); LATS, large tumor suppressor, homolog 2 (Drosophila); LATS1 +LATS2 (phospho T1079 + T1041); p-LATS1 +LATS2(Thr1079 +Thr1041); RGD1564085; Serine/threonine protein kinase LATS1; WARTS; WARTS protein kinase; wts; 4932411G09Rik; AV277261; AW208599; AW228608; FLJ13161; LATS1_HUMAN.
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG
免疫原:
详见说明书
货号:
Hz-R7913
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Rabbit  Anti-phospho-LATS1+LATS2 (Thr1079 +Thr1041) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-LATS1+LATS2 (Thr1079 +Thr1041)

IR:Immunogen Range:EF(P-T)FR

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:26524

Swiss Prot:O95835

Source:KLH conjugated synthesised phosphopeptide derived from human LATS1 around the phosphorylation site of Thr1079:EF(P-T)FR 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Acts as a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. Negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. Negative regulator of the androgen receptor.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit

image.png
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!

phospho-LATS1+LATS2 ;LATS1 +LATS2 (phosph;Serine/threonine pro;KPM;homolog 1 (Drosophil;p-LATS1 +LATS2(Thr10;WARTS;LATS1_HUMAN;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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