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  • Anti-Phospho-MDM2 (Ser186)  antibody-磷酸化双微体2癌基因抗体

Anti-Phospho-MDM2 (Ser186) antibody-磷酸化双微体2癌基因抗体

Phospho-MDM2 (Ser186)
1280 50ul 起订
1980 100ul 起订
2900 200ul 起订
上海 更新日期:2024-07-22

上海沪震实业有限公司

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联系人:陈环环
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产品详情:

中文名称:
Anti-Phospho-MDM2 (Ser186) antibody-磷酸化双微体2癌基因抗体
英文名称:
Phospho-MDM2 (Ser186)
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
MDM2 (phospho S186); p-MDM2 (phospho S186); MDM2(phospho S186); MDM2 (phospho Ser186); p-MDM2 (S186); p-MDM2 (Ser186); Double minute 2 protein; Hdm 2; HDM2; MDM 2; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa; MDM2BP; Mouse Double Minute 2; MTBP; Murine Double Minute Chromosome 2; Oncoprotein Mdm2; p53 Binding Protein Mdm2; Ubiquitin protein ligase E3 Mdm2; MDM2_HUMAN; E3 ubiquitin-protein ligase Mdm2.
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG
免疫原:
详见说明书
货号:
Hz-R5471
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Rabbit  Anti-Phospho-MDM2 (Ser186) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Phospho-MDM2 (Ser186)

IR:Immunogen Range:HK(p-S)D-NH2

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4193

Swiss Prot:Q00987

Source:KLH conjugated Synthesised phosphopeptide derived from human MDM2 around the phosphorylation site of Ser186:HK(p-S)D-NH2 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Inhibits TP53/p53- and TP73/p73-mediated cell cyclearrest and apoptosis by binding its transcriptional activation domain. Functions as a ubiquitin ligase E3, in the presence of E1 and E2, toward p53 and itself. Permits the nuclear export of p53 and targets it for proteasome-mediated proteolysis. Binds p53, p73, ARF(P14), ribosomal protein L5 and specifically to RNA. Can interact also with retinoblastoma protein(RB), E1A-associated protein EP300 and the E2F1 transcription factor. Forms a ternary complex with TP53/p53 and WWOX. Interacts with CDKN2AIP, MTBP, TRBG1 and USP7. Isoform Mdm2-F does not interact with TP53/p53. Interacts with PYHIN1. Interacts with, and ubiquitinates HIV-1 Tat. Belongs to the MDM2/MDM4 family.

Sheep

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)

Cross Reactive Species:Human
Chicken
Dog
Pig
Cow
Horse
Rabbit
Guinea Pig

image.png
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!

Phospho-MDM2 (Ser186;MDM2 (phospho S186);p-MDM2 (phospho S186;MDM2(phospho S186);HDM2;Mdm2;MDM2BP;MDM2_HUMAN;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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