Anti-CMA1 antibody-肥大细胞类糜蛋白酶1抗体

Rabbit  Anti-CMA1 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:CMA1

IR:Immunogen Range:28-42/247

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:1215

Swiss Prot:P23946

Source:KLH conjugated synthetic peptide derived from human CMA1:28-42/247 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Sheep
Guinea Pig

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！