抑制剂多肽H-Leu-Ser-Lys-Leu-NH2/283609-79-0/Inhibitor of Thrombospondin TSP-1

Product Name：LSKL

CAS No.：283609-79-0

Synonyms：Inhibitor of Thrombospondin TSP-1；抑制剂多肽LSKL

Catalog No.：209P03

Brand：HongTide（上海鸿肽生物）

Description：LSKL是由4个氨基酸组成的抑制剂多肽，是一种与潜伏期相关肽衍生的多肽，可抑制TGF-β的血小板反应蛋白（TSP-1）活化，并防止肝损伤、纤维化；同时，LSKL可以轻松穿越血脑屏障，减轻脑积水；LSKL可通过拮抗TSP-1来成功减弱TGF-β-Smad信号的激活，但不能降低TSP-1的蛋白表达；LSKL还能促进肝切除术后肝细胞增殖。

LSKL is an inhibitor peptide composed of four amino acids, which is derived from latency related peptides and can inhibit TGF- β Activation of platelet reactive protein (TSP-1) and prevention of liver injury and fibrosis; At the same time, LSKL can easily cross the Blood–brain barrier to reduce Hydrocephalus; LSKL can successfully weaken TGF by antagonizing TSP-1- β- The activation of Smad signal cannot reduce the protein expression of TSP-1; LSKL can also promote hepatocyte proliferation after Hepatectomy.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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