Anti-NQO1 antibody-醌氧化还原酶抗体

Rabbit  Anti-NQO1 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:NQO1

IR:Immunogen Range:201-274/274

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:18104

Swiss Prot:Q64669

Source:KLH conjugated synthetic peptide derived from mouse NQO1:201-274/274 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)

Cross Reactive Species:Human
Mouse
Rat

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！