Anti-Ribonuclease 3/ECP antibody-嗜酸性粒细胞阳离子蛋白抗体

Rabbit  Anti-Ribonuclease 3/ECP Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Ribonuclease 3/ECP

IR:Immunogen Range:45-160/160

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6037

Swiss Prot:P12724

Source:KLH conjugated synthetic peptide derived from human Ribonuclease 3:45-160/160 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:ECP is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
ICC(1:100-500)

Cross Reactive Species:Human
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仅供科研使用。不能用于人和动物治疗等其它临床诊断用！