Anti-MGLUR3 antibody-代谢型谷氨酸受体-3抗体

Rabbit  Anti-MGLUR3 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:MGLUR3

IR:Immunogen Range:365-460/879

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2913

Swiss Prot:Q14832

Source:KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3:365-460/879 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(5μg/Test)

Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Rabbit

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！