Anti-PFKFB3/PFK2 antibody-果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

Rabbit  Anti-PFKFB3/PFK2 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:PFKFB3/PFK2

IR:Immunogen Range:401-520/520

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5209

Swiss Prot:Q16875

Source:KLH conjugated synthetic peptide derived from human PFKFB3:401-520/520 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Guinea Pig

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！