荧光 HIV-1 蛋白酶底物/127134-13-8/Dabcyl-Gaba-SQNYPIVQ-Edans

Product Name：Dabcyl-Gaba-SQNYPIVQ-Edans  

CAS No.：127134-13-8

Synonyms：淬灭受体组合肽

Catalog No.：162P11

Brand：HongTide（上海鸿肽生物）

Description：Dabcyl-Gaba-SQNYPIVQ-Edans是荧光HIV-1蛋白酶底物多肽，由一个八肽与一个荧光供体（EDANS）和一个淬灭受体（DABCYL）组成，连接在 COOH-和 NH2-末端。Dabcyl-Gaba-SQNYPIVQ-Edans的序列中插入 γ-Abu 间隔物以避免大受体对底物结合的潜在空间位阻，这种 FRET 底物在 Tyr-Pro 键上被 HIV-1 蛋白酶切割，导致荧光强度随时间增加；Dabcyl-Gaba-SQNYPIVQ-Edans的激发波长为 340 nm，发射波长为 490 nm。

Dabcyl-Gaba-SQNYPIVQ-Edans is a fluorescent HIV-1 protease substrate peptide, which is composed of an octapeptide, a fluorescent donor (EDANS) and a quenched receptor (DABCYL), connected to the COOH - and NH2- terminals. Insertion into the sequence of Dabcyl Gaba SQNYPIVQ Edans γ- Abu spacer to avoid the Potential space steric hindrance of large receptors to substrate binding. This FRET substrate is cut by HIV-1 protease on the Tyr-Pro bond, resulting in an increase in fluorescence intensity over time; The excitation wavelength of Dabcyl-Gaba-SQNYPIVQ-Edans is 340 nm, and the emission wavelength is 490 nm.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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