SCARB1/Scavenger Receptor BI 高密度脂蛋白受体/清道夫受体抗体

Rabbit  Anti-SCARB1/Scavenger Receptor BI Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:SCARB1/Scavenger Receptor BI

IR:Immunogen Range:21-100/552

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:949

Swiss Prot:Q8WTV0

Source:KLH conjugated synthetic peptide derived from human CD36L1:21-100/552 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
Horse
Rabbit

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！