IDH2 线粒体异柠檬酸脱氢酶抗体

Rabbit  Anti-IDH2 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:IDH2

IR:Immunogen Range:251-350/452

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3418

Swiss Prot:P48735

Source:KLH conjugated synthetic peptide derived from human IDH2:251-350/452 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(0.2ug/test)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Horse

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！