CTH 胱硫醚γ裂解酶抗体

Rabbit  Anti-CTH Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:CTH

IR:Immunogen Range:51-150/405

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:1491

Swiss Prot:P32929

Source:KLH conjugated synthetic peptide derived from human CTH/CSE/Cystathionase:51-150/405 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.
Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Rabbit

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！