PDGF Receptor beta 血小板源性生长因子受体B/PDGFRβ抗体

Rabbit  Anti-PDGF Receptor beta Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:PDGF Receptor beta

IR:Immunogen Range:981-1066/1106

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5159

Swiss Prot:P09619

Source:KLH conjugated synthetic peptide derived from human PDGF-R-B:981-1066/1106 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！