RUNX2 核心结合因子α1/成骨特异性转录因子/Cbfα1抗体

Rabbit  Anti-RUNX2 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:RUNX2

IR:Immunogen Range:202-300/521

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:860

Swiss Prot:Q13950

Source:KLH conjugated synthetic peptide derived from human RUNX2:202-300/521 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！