Adiponectin Receptor 1 脂联素受体1抗体

Rabbit  Anti-Adiponectin Receptor 1 Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Adiponectin Receptor 1

IR:Immunogen Range:241-270/375

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:51094

Swiss Prot:Q96A54

Source:KLH conjugated synthetic peptide derived from human Adiponectin Receptor 1:241-270/375 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Acrp30 is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes. This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR- . Cloning of complementary DNAs encoding adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2) have shown that AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Rabbit

本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！