人光感受器间类视黄醇结合蛋白 (IRBP)片段多肽/IRBP (651-670) (human)

Product Name：hIRBP651-670

CAS No.：N/A

Synonyms：IRBP (651-670) (human)；人光感受器间类视黄醇结合蛋白 (IRBP)片段多肽

Catalog No.：218P338

Brand：HongTide（上海鸿肽生物）

Description：hIRBP651-670是人光感受器间类视黄醇结合蛋白 (IRBP) 的氨基酸残基 651 至 670，多肽序列中含有20个氨基酸，已被鉴定为新的葡萄膜生成表位。hIRBP651-670对 H-2b 单倍型小鼠具有致葡萄膜炎性，并在C57BL/6小鼠中引起实验性自身免疫性葡萄膜炎（EAU），其严重程度和发生率高于先前表征的 IRBP（1-20）（人 ) 表位。 与 IRBP (1-20)（人）和 IRBP (651-670) 人共同免疫是相加的，但不是协同的。hIRBP651-670似乎是从天然 IRBP 的保守区域自然加工的表位。

HIRBP651-670 is the amino acid residue 651-670 of human photoreceptor Retinol like binding protein (IRBP). The peptide sequence contains 20 amino acids and has been identified as a new Uvea generating epitope. HIRBP651-670 has Uveitis inducing effect on H-2b Haplotype mice, and causes experimental autoimmune Uveitis (EAU) in C57BL/6 mice. Its severity and incidence are higher than previously characterized IRBP (1-20) (human) epitope. The co immunity with IRBP (1-20) and IRBP (651-670) individuals is additive, but not synergistic. HIRBP651-670 seems to be a naturally processed epitope from the conserved region of natural IRBP.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

上海鸿肽生物科技有限公司

手机： +86-18018095145 （同微信号）

QQ: 3259098395

邮箱：sales1@hongtide.com