R-2,3-二羟基异戊酸 19451-56-0

R-2,3-二羟基异戊酸是支链氨基酸合成途径的一个中间代谢产物，是合成缬氨酸和异亮氨基酸代谢途径的中间代谢产物，本产品为生物过程生产，具有良好的手型。HMDB ID HMDB0012141

(R) 2,3-Dihydroxy-isovalerate is an intermediate in valine, leucine and isoleucine biosynthesis. The pathway of valine biosynthesis is a four-step pathway that shares all of its steps with the parallel pathway of isoleucine biosynthesis. These entwined pathways are part of the superpathway of leucine, valine, and isoleucine biosynthesis , that generates not only isoleucine and valine, but also leucine. (R) 2,3-Dihydroxy-isovalerate is generated from 3-Hydroxy-3-methyl-2-oxobutanoic acid via the enzyme ketol-acid reductoisomerase (EC 1.1.1.86) then it is converted to 2-Oxoisovalerate via the dihydroxy-acid dehydratase (EC:4.2.1.9).