FRET底物多肽/932391-88-3/MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2

Product Name：MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2

CAS No.：932391-88-3

Synonyms：FRET底物多肽

Catalog No.：218P324

Brand：HongTide（上海鸿肽生物）

Description：MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 是严重急性呼吸综合征冠状病毒主蛋白酶 (SARS-CoV Mpro) 的 FRET 底物多肽，序列中含有10个氨基酸。 MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 底物序列来源于具有 AVLQSGFRK 序列的 SARS-CoV Mpro N 末端自动加工位点的残基 P4-P5'。 MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 的 Q4 和 S5 之间的酶促裂解释放出高荧光的 7-甲氧基香豆素 (Mca) 基团，该基团受到 2,4-二硝基苯基 (Dnp) 内部猝灭剂的影响，从而产生大量荧光强度增加。

MCA-AVLQSGFR Lys (Dnp) Lys NH2 is a FRET substrate peptide of the main protease of severe acute respiratory syndrome coronavirus (SARS-CoV Mpro), with a sequence containing 10 amino acids. The substrate sequence of MCA-AVLQSGFR-Lys (Dnp) - Lys-NH2 is derived from the residue P4-P5 'of SARS-CoV Mpro N-terminal automatic processing site with AVLQSGFRK sequence. The enzymatic cleavage between Q4 and S5 of MCA-AVLQSGFR-Lys (Dnp) - Lys-NH2 explains that it emits a highly fluorescent 7-neneneba methoxy Coumarin (Mca) group, which is affected by the internal quenching agent of 2,4-dinitrophenyl (Dnp), resulting in a large increase in fluorescence intensity.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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