受体拮抗剂多肽GR 231118/158859-98-4/Neuropeptide Y Antagonist

Product Name：Neuropeptide Y Antagonist

CAS No.：158859-98-4

Synonyms：受体拮抗剂多肽GR 231118

Catalog No.：218P312

Brand：HongTide（上海鸿肽生物）

Description：Neuropeptide Y Antagonist是一种有效的神经肽 Y (NPY) Y1 受体拮抗剂多肽（rY1 和 hY1 受体的 pA2 = 10 和 10.5），序列中是一个二聚体多肽，通过酰胺键形成的二聚体多肽。Neuropeptide Y Antagonist也是一种有效和选择性的 NPY Y4 受体激动剂（rY2、hY4 和 rY5 受体的 pEC50 值分别为 6.0、8.6 和 6.1），由同一段序列通过酰胺键形成的二聚体多肽。在体内抑制大鼠的食物摄入，Neuropeptide Y Antagonist在体外也对神经肽 FF (NPFF) 受体具有亲和力 (Ki = 43-73 nM)。

Neuropeptide Y Antagonist is an effective Neuropeptide Y (NPY) Y1 receptor antagonist peptide (pA2 of rY1 and hY1 receptors=10 and 10.5). The sequence is a dimer peptide formed by amide bond. Neuropeptide Y Antigonist is also an effective and selective NPY Y4 receptor agonist (pEC50 values of 6.0, 8.6, and 6.1 for rY2, hY4, and rY5 receptors, respectively), a dimeric peptide formed from the same sequence through amide bonds. Neuropeptide Y Antagonist also has affinity for Neuropeptide FF (NPFF) receptor in vitro (Ki=43-73 nM) by inhibiting food intake of rats in vivo.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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