双重肽激动剂多肽Cotadutide/1686108-82-6/Cotadutide acetate

Product Name：Cotadutide acetate

CAS No.：1686108-82-6

Synonyms：双重肽激动剂多肽Cotadutide

Catalog No.：218P269

Brand：HongTide（上海鸿肽生物）

Description：Cotadutide acetate是胰高血糖素样肽-1 (GLP-1)和胰高血糖素受体 (glucagon receptor) 的有效双重肽激动剂多肽，序列中含有31个氨基酸，多肽的N端由棕榈酸封闭，多肽结构中含有一个酰胺键组成的环状结构，EC50 值分别为 6.9 pM 和 10.2 pM。Cotadutide acetate有促进减肥和控制血糖的能力，有潜力用于肥胖症和 2 型糖尿病 (T2D) 的研究。

Cotadutide acetate is an effective dual peptide agonist peptide of glucagon like peptide-1 (GLP-1) and glucagon receptor. The sequence contains 31 amino acids. The N-terminal of the polypeptide is blocked by palmitic acid. The peptide structure contains a ring structure composed of an amide bond. The EC50 values are 6.9 pM and 10.2 pM, respectively. Cotadutide acetate has the ability to promote weight loss and control blood sugar, and has the potential to be used in the study of obesity and type 2 diabetes (T2D).

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	Pal-EHSQGTFTSDKSEYLDSERARDFVAWLEAGG (Amide bridge: Glu1-Lys10)
Sequence(3-letter code)	Pal-Glu-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Lys-Ser-Glu-Tyr-Leu-Asp-Ser-Glu-Arg-Ala-Arg-Asp-Phe-Val-Ala-Trp-Leu-Glu-Ala-Gly-Gly-OH(Amide bridge: Glu1-Lys10)
Peptide Structure
Molecular Formula	C169H256N42O57
Molecular Weight	3788.14

订购联系方式：

上海鸿肽生物科技有限公司

手机： +86-18018095145 （同微信号）

QQ: 3259098395

邮箱：sales1@hongtide.com