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网站主页 ANTI-INSULIN RECEPTOR ALPHA ANTIBODY-胰岛素受体Α抗体 Anti-Insulin Receptor alpha antibody-胰岛素受体α抗体
  • Anti-Insulin Receptor alpha antibody-胰岛素受体α抗体

Anti-Insulin Receptor alpha antibody-胰岛素受体α抗体

Insulin Receptor alpha
￥1098 50ul 起订
￥1880 100ul 起订
￥2900 200ul 起订
上海 更新日期：2024-11-27

上海沪震实业有限公司

VIP3年
联系人：陈环环
电话：021-60345367拨打
手机：13916550749 拨打
邮箱：sales@shzbio.com

产品详情:

中文名称：
Anti-Insulin Receptor alpha antibody-胰岛素受体α抗体
英文名称：
Insulin Receptor alpha
品牌：
沪震生物
产地：
中国/上海
保存条件：
-20°C
纯度规格：
> 99%
产品类别：
抗体 一抗
抗体名：
CD 220; CD220; CD220 antigen; HHF 5; HHF5; INSR; IR; 4932439J01Rik; ALPHA SUBUNIT INSULIN RECEPTOR; D630014A15Rik; INSULIN RECEPTOR; INSULIN RECEPTOR KINASE; INSULIN RPTK; IR ALPHA; IRK; INSR_HUMAN.
靶点：
详见说明书
宿主：
Rabbit
适应物种：
详见说明书
克隆性：
详见说明书
浓度：
1mg/ml
应用范围：
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物：
详见说明书
形态：
液体
亚型：
IgG1
免疫原：
详见说明书
货号：
Hz-R0047
用途范围：
科研使用
规格：
50ul/100ul/200ul
是否进口：
否
是否单克隆：
详见说明书p55
保质期：
12个月
抗原来源：
详见说明书
标记物：
详见说明书
产品用途：
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.


Host:Rabbit

Target Protein:Insulin Receptor alpha

IR:Immunogen Range:701-760/1382

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3643

Swiss Prot:P06213

Source:KLH conjugated synthetic peptide derived from human Insulin Receptor alpha:701-760/1382 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.
Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(0.2μg/Test)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep

搜狗截图23年05月22日0943_461.png本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
CD220;CD 220;HHF5;HHF 5;INSR;4932439J01Rik;IR;Insulin Receptor alp;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品：试剂盒，ELISA试剂盒，抗体，重组蛋白，血清，胎牛血清，细胞，原代细胞 细胞培养试剂，常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ￥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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