莫瑞伐定/944252-63-5/Murepavadin/POL7080

Product Name：Murepavadin

CAS No.：944252-63-5

Synonyms：POL7080；POL 7080；POL-7080；莫瑞伐定

Catalog No.：218P243

Brand：HongTide（上海鸿肽生物）

Description：Murepavadin是一种靶向革兰氏阴性菌外膜蛋白的新型抗生素多肽，序列中含有大量的碱性氨基酸，包含14个氨基酸，靶向脂多糖转运蛋白D(LptD)。Murepavadin可用于治疗院内肺炎，目前已处于临床试验III期。

Murepavadin is a novel antibiotic peptide that targets the outer membrane protein of Gram negative bacteria. The sequence contains a large number of basic amino acids, including 14 amino acids, targeting lipopolysaccharide transporter D (LptD). Murepavadin can be used to treat hospital pneumonia and is currently in phase III of a clinical trial.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	cyclo[AS-d-P-PTWI-Dab-Orn-D-Dab-Dab-W-Dab-Dab]
Sequence(3-letter code)	cyclo[Ala-Ser-D-Pro-Pro-Thr-Trp-Ile-Dab-Orn-D-Dab-Dab-Trp-Dab-Dab]
Peptide Structure
Molecular Formula	C73H112N22O16
Molecular Weight	1553.84

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