艾卡拉肽/460738-38-9/Ecallantide/DX 88

Product Name：Ecallantide

CAS No.：460738-38-9

Synonyms：DX 88；艾卡拉肽

Catalog No.：218P229

Brand：HongTide（上海鸿肽生物）

Description：Ecallantide是一条由60个氨基酸组成的多肽，含有序列中3对二硫键。Ecallantide用于遗传性血管水肿（HAE）突发或致命性积液的治疗研究，是在美国上市的第二种治疗HAE发作的药物多肽。

Ecallantide is a peptide composed of 60 amino acids, containing 3 pairs of disulfide bonds in the sequence. Ecallantide is the second drug peptide available in the United States for the treatment of sudden or fatal fluid accumulation in hereditary angioedema (HAE).

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	EAMHSFCAFKADDGPCRAAHPRWFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD(Disulfide bridge：Cys7-Cys57;Cys16-Cys40;Cys32-Cys53)
Sequence(3-letter code)	H-Glu-Ala-Met-His-Ser-Phe-Cys-Ala-Phe-Lys-Ala-Asp-Asp-Gly-Pro-Cys-Arg-Ala-Ala-His-Pro-Arg-Trp-Phe-Phe-Asn-Ile-Phe-Thr-Arg-Gln-Cys-Glu-Glu-Phe-Ile-Tyr-Gly-Gly-Cys-Glu-Gly-Asn-Gln-Asn-Arg-Phe-Glu-Ser-Leu-Glu-Glu-Cys-Lys-Lys-Met-Cys-Thr-Arg-Asp-OH(Disulfide bridge：Cys7-Cys57;Cys16-Cys40;Cys32-Cys53)
Peptide Structure
Molecular Formula	C305H442N88O91S8
Molecular Weight	7053.89

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