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网站主页 Forkhead box protein O1A Anti-FOXO1A antibody-叉头蛋白O1抗体
  • Anti-FOXO1A  antibody-叉头蛋白O1抗体

Anti-FOXO1A antibody-叉头蛋白O1抗体

FOXO1A
1138 50ul 起订
1880 100ul 起订
2900 200ul 起订
上海 更新日期:2024-08-15

上海沪震实业有限公司

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联系人:陈环环
电话:021-60345367拨打
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邮箱:sales@shzbio.com

产品详情:

中文名称:
Anti-FOXO1A antibody-叉头蛋白O1抗体
英文名称:
FOXO1A
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
FKH1; FKHR; FKHR; Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma); Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma); Forkhead box O1; Forkhead box protein O1; Forkhead box protein O1A.
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG1
免疫原:
详见说明书
货号:
Hz-R9439
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书p55
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Host:Rabbit

Target Protein:FOXO1A

IR:Immunogen Range:165-270/655

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2308

Swiss Prot:Q12778

Source:KLH conjugated synthetic peptide derived from human FKHR:165-270/655 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. These translocations result in the fusion of the amino terminus of Pax-3 or Pax-7, including the paired box and homeodomain DNA-binding domains, with the carboxy-terminus of FKHR, which contains a transcriptional activation domain. The Pax-3/FKHR fusion protein appears to function as an oncogenic transcription factor that enhances the activation of normal Pax-3 target genes.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit

搜狗截图23年05月12日1442_274.png

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!                        


FKH1;FKHR;FKHR;FOXO1A; Forkhead box O1;Forkhead box protein;Forkhead box protein;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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