Anti-STAT6 antibody -信号转导和转录激活因子6抗体

Host:Rabbit

Target Protein:STAT6

IR:Immunogen Range:601-700/841

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6778

Swiss Prot:P42226

Source:KLH conjugated synthetic peptide derived from human STAT6:601-700/841 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat

                                                                                                                                                  本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！