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  • Anti-SKP2 antibody  -细胞S期激酶相关蛋白2抗体

Anti-SKP2 antibody -细胞S期激酶相关蛋白2抗体

SKP2
1098 50ul 起订
1880 100ul 起订
2900 200ul 起订
上海 更新日期:2024-07-16

上海沪震实业有限公司

VIP2年
联系人:陈环环
电话:021-60345367拨打
手机:13916550749 拨打
邮箱:sales@shzbio.com

产品详情:

中文名称:
Anti-SKP2 antibody -细胞S期激酶相关蛋白2抗体
英文名称:
SKP2
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
p45skp2; skp2p45; p45; skp2 p45;S-phase kinase-associated protein 2; SKP2; CDK2/Cyclin A associated protein p45; Cyclin A/CDK2 associated protein p45; F box protein Skp2; F box/LRR repeat protein 1; FBL 1; FBL1; FBXL 1; FBXL1; FLB 1; FLB1; MGC1366; SKP2_HUMAN.
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG1
免疫原:
详见说明书
货号:
Hz-R1096
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Host:Rabbit

Target Protein:SKP2

IR:Immunogen Range:351-424/424

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6502

Swiss Prot:Q13309

Source:KLH conjugated synthetic peptide derived from human Skp2:351-424/424 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1L, CDT1, RBL2, MLL, CDK9, RAG2, FOXO1A, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. [PATHWAY] Protein modification; protein ubiquitination. [SUBUNIT] Part of the SCF(SKP2) complex consisting of CUL1, RBX1, SKP1 and SKP2. Interacts directly with CUL1 and SKP1. Interacts with CKS1. Interacts with the cyclin A-CDK2 complex. Interacts with ORC1L, phosphorylated CDT1, phosphorylated RBL2, ELF4, phosphorylated RAG2, FOXO1A, UBP43, MYC, TOB1, TAL1 and MLL. [SIMILARITY] Contains 1 F-box domain. [SIMILARITY] Contains 8 LRR (leucine-rich) repeats.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
Rabbi

搜狗截图23年05月11日1147_161.png                                                                                                                                                  本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!


p45skp2;skp2p45;skp2 ;p45;SKP2;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

成立日期 (11年)
注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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