Anti-IL6ST/CD130 antibody-白细胞介素6受体β/CD130抗体

Host:Rabbit

Target Protein:IL6ST/CD130

IR:Immunogen Range:651-750/917

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3572

Swiss Prot:P40189

Source:KLH conjugated synthetic peptide derived from human IL6R beta:651-750/917 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1µg/Test)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！