Anti-Growth hormone receptor antibody-生长激素受体抗体

Host:Rabbit

Target Protein:Growth hormone receptor

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:2690

Swiss Prot:P10912

Source:KLH conjugated synthetic peptide derived from human Growth hormone receptor: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500)
IHC-P(1:50-200)
ICC(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
.

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！