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Anti-phospho-IRS1 antibody-磷酸化胰岛素受体底物-1抗体

phospho-IRS1 (Ser636 + Ser639)
1280 50ul 起订
1980 100ul 起订
2900 200ul 起订
上海 更新日期:2024-12-02

上海沪震实业有限公司

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产品详情:

中文名称:
Anti-phospho-IRS1 antibody-磷酸化胰岛素受体底物-1抗体
英文名称:
phospho-IRS1 (Ser636 + Ser639)
品牌:
沪震生物
产地:
中国/上海
保存条件:
-20°C
纯度规格:
> 99%
产品类别:
抗体 一抗
抗体名:
IRS1 (phospho S636); p-IRS1 (phospho S636); IRS1 (phospho S639); p-IRS1 (phospho S639); IRS-1(Phospho-Ser636); IRS-1(Phospho-Ser639); p-IRS1; IRS1(phospho-Ser636/639); IRS1_HUMAN; Insulin receptor substrate 1; IRS-1; IRS 1;
靶点:
详见说明书
宿主:
Rabbit
适应物种:
详见说明书
克隆性:
详见说明书
浓度:
1mg/ml
应用范围:
ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /test ICC=1:100 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
标识物:
详见说明书
形态:
液体
亚型:
IgG1
免疫原:
详见说明书
货号:
HZ-R3201
用途范围:
科研使用
规格:
50ul/100ul/200ul
是否进口:
是否单克隆:
详见说明书
保质期:
12个月
抗原来源:
详见说明书
标记物:
详见说明书
产品用途:
ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /test ICC=1:100 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Host:Rabbit

Target Protein:phospho-IRS1 (Ser636 + Ser639)

IR:Immunogen Range:PM(p-S)PK(p-S)VS

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3667

Swiss Prot:P35568

Source:KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser636/639:PM(p-S)PK(p-S)VS 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(1μg /test)
ICC(1:100)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit

搜狗截图23年04月26日1120_174.png


本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!

















































phospho-IRS1; IRS-1; IRS 1;p-IRS1;IRS1 ;

公司简介

上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。

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注册资本 100万元整
员工人数 10-50人
年营业额 ¥ 100万以内
经营模式 工厂,试剂,定制,服务
主营行业 生化试剂,细胞培养,蛋白组学,分子生物学,细胞生物学

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