Anti-ERK2 antibody -丝裂原活化蛋白激酶2重组兔单克隆抗体

Host:Rabbit

Target Protein:ERK2

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:5594

Swiss Prot:P28482

Source:Recombinant human ERK2 protein, around C-terminal 150aa: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1ug/Test)
ICC(1:100)
IF(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
.