Anti-ACE2 antibody-重组兔血管紧张素转换酶单克隆抗体

Host:Rabbit

Target Protein:ACE2

IR:Immunogen Range:180-240/805

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:59272

Swiss Prot:Q9BYF1

Source:KLH conjugated synthetic peptide derived from human ACE2:180-240/805 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Background:Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension.
ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50)
IF(1:100-200)

Cross Reactive Species:Human
Mouse
Rat

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！