Anti-S100 beta antibody-S100B蛋白重组兔单克隆抗体

Host:Rabbit

Target Protein:S100 beta

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:6285

Swiss Prot:P04271

Source:KLH conjugated synthetic peptide derived from human S100B: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
Zebrafish

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！