Anti-SCARB1-高密度脂蛋白受体/清道夫受体重组兔单克隆抗体

Host:Rabbit

Target Protein:SCARB1/Scavenger Receptor BI

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:949

Swiss Prot:Q8WTV0

Source:KLH conjugated synthetic peptide derived from human SCARB1/Scavenger Receptor BI: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:200-500)
IHC-F(1:200-500)
ICC(1:50-200)

Cross Reactive Species:Human
Mouse
Rat

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！