内皮素-1/117399-94-7/Endothelin-1, human

Product Name：Endothelin-1, human

CAS No.：117399-94-7

Synonyms：Endothelin 1 (swine, human)；内皮素-1

Catalog No.：137P15

Brand：HongTide（上海鸿肽生物）

Description：Endothelin 1 (swine, human) 是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂多肽，序列中含有15个氨基酸，并且包含两对二硫键，由于其特殊结构，化学合成方法难度很大。Endothelin 1 通过两种类型受体ETA和ETB发挥作用。Endothelin-1 (ET-1)是一种有效的内源性血管收缩剂，主要由内皮细胞分泌。Endothelin-1通过两种类型的受体起作用：ETA 和 ETB。 除了血管收缩作用外，Endothelin-1还会导致血管细胞纤维化并刺激活性氧的产生。据称Endothelin-1可诱导促炎机制，增加超氧阴离子的产生和细胞因子的分泌。

Endothelin 1 (swine, human) is a synthetic peptide with human and porcine endothelin 1 sequences. It is an effective endogenous vasoconstrictor peptide, containing 15 amino acids and two pairs of disulfide bonds. Due to its unique structure, chemical synthesis methods are very difficult. Endothelin 1 works through two types of receptors, ETA and ETB. Endothelin-1 (ET-1) is an effective endogenous vasoconstrictor mainly secreted by endothelial cells. Endothelin-1 works through two types of receptors: ETA and ETB. In addition to vasoconstriction, Endothelin-1 can also cause vascular cell fibrosis and stimulate the production of reactive oxygen species. It is said that Endothelin-1 can induce pro-inflammatory mechanisms, increase the production of superoxide anions and the secretion of cytokines.

Purity (HPLC) ≥95.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

上海鸿肽生物科技有限公司

手机： +86-18018095145 （同微信号）

QQ: 3259098395

邮箱：sales1@hongtide.com