人源性抗菌肽LL-37 FKR/913736-94-4/LL-37 (17-37)

Product Name：LL-37 FKR

CAS No.：913736-94-4

Synonyms：LL-37 (17-37)；Cationic Antimicrobial Protein 18 (150-170) (human),hCAP-18 (150-170)；人源性抗菌肽LL-37 FKR

Catalog No.：112P47

Brand：HongTide（上海鸿肽生物）

Description：LL-37 是人体内发现的唯一的一种Cathelicidin 类抗菌肽，LL-37是由前体hCAP-18 经丝氨酸蛋白酶3剪切后产生。大量研究发现，LL-37 可在卵巢癌、肺癌、恶性黑色素瘤、皮肤鳞状细胞癌、前列腺癌等肿瘤中发挥促癌作用；而在胃癌、结直肠癌、白血病等肿瘤中发挥抑癌作用，因此对LL-37的研究具有很大的潜力。LL-37 FKR是从LL-37序列中选取第17个氨基酸至第37个氨基酸片段，保留了大部分的生理学功能。

LL-37 is the only Catalicidin class antimicrobial peptide found in the human body, and is produced by the precursor hCAP-18 after being cleaved by serine protease 3. A large number of studies have found that LL-37 can play a cancer promoting role in ovarian cancer, lung cancer, malignant melanoma, skin squamous cell carcinoma, prostate cancer and other tumors; And it plays an inhibitory role in tumors such as gastric cancer, colorectal cancer, and leukemia, so the research on LL-37 has great potential. LL-37 FKR selects the 17th to 37th amino acid fragments from the LL-37 sequence, preserving most of its physiological functions.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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