Product Name：Ularitide Acetate
CAS No.：118812-69-4；115966-23-9
Synonyms：Urodilatin (human)；Urodilatin CCC/ANP (95-126)；乌拉立肽；乌罗地丁,人类
Catalog No.：177P05
Brand：HongTide（上海鸿肽）
Description：乌拉立肽（乌罗地丁,人类）是32个氨基酸残基组成的促尿钠排泄环肽，序列中含有一对二硫键，在一些临床实验中已证实乌拉立肽能够降低肾脏对尿液的重吸收。同时以乌拉立肽为主要原料的药物能降低心脏充盈压力和改善呼吸困难，且对DHF患者的肾脏功能没有明显的不良影响。
Ularitide (Urodilatin human) is a cyclic peptide composed of 32 amino acid residues that promote sodium excretion and contains a pair of disulfide bonds in its sequence. In some clinical experiments, it has been confirmed that Ularitide can reduce renal reabsorption of urine. At the same time, drugs using urethane as the main raw material can reduce cardiac filling pressure and improve dyspnea, and have no significant adverse effects on renal function in patients with DHF.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | TAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY(Disulfide bridge Cys11-Cys27) |
Sequence(3-letter code) | H-Thr-Ala-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH(Disulfide bridge Cys11-Cys27) |
Peptide Structure | 
|
Molecular Formula | C145H234N52O44S3 |
Molecular Weight | 3505.97 |
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